Intended for healthcare professionals

Minerva

Immune checkpoint inhibitors . . . and other stories

BMJ 2025; 388 doi: https://doi.org/10.1136/bmj.r378 (Published 06 March 2025) Cite this as: BMJ 2025;388:r378

Digoxin in atrial fibrillation

For rate control in older people with established atrial fibrillation, low dose digoxin saves £500 each year compared with beta blockers. It’s not the cost of the drugs—both digoxin and beta blockers are cheap—but the number of adverse events in those taking digoxin is substantially lower, so savings are made because there’s less use of primary and secondary healthcare. Patient reported quality of life is better with digoxin too (Heart doi:10.1136/heartjnl-2024-324761).

Cardiovascular disease after twin pregnancies

Pregnancy places considerable demands on the maternal cardiovascular system. These demands are higher still …

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